Group leader: Lorenzo Malavasi
In this research field we develop novel semiconducting nanocrystalline materials (quantum dots) for nanomedicine applications, particularly for the in-vitro and in-vivo multiplexed diagnostic. We focus on metal halide perovskite nanocrystals which have extremely high quantum yields and an easy tuning of the emission wavelengths. The activity is centered around the preparation of optimized nanocrystals and their inclusion into a biocompatible polymer (such as PLGA or PLA) which allows a further surface functionalization for cellular recognition. The final aim is to achieve highly emissive nanosystems showing enhanced stability in body fluids and with a vast gamut of emission frequencies. The research activity is carried out in collaboration with the Department of Pharmaceutical Science.
Sandri, G., Rossi, S., Bonferoni, M.C., Miele, D., Faccendini, A., Del Favero, E., Di Cola, E., Icaro Cornaglia, A., Boselli, C., Luxbacher, T., Malavasi, L., Cantu, L., Ferrari, F.,
Chitosan/glycosaminoglycan scaffolds for skin reparation
(2019) Carbohydrate Polymers, 220, pp. 219-227. DOI: 10.1016/j.carbpol.2019.05.069
Chiara, R., Ciftci, Y.O., Queloz, V.I.E., Nazeeruddin, M.K., Grancini, G., Malavasi,
L., Green-emitting lead-free Cs4SnBr6 zero-dimensional perovskite nanocrystals with improved air stability,
(2020) Journal of Physical Chemistry Letters, 11, pp. 618-623. DOI: 10.1021/acs.jpclett.9b03685
Veronese, A., Patrini, M., Bajoni, D., Ciarrocchi, C., Quadrelli, P., Malavasi, L.,
Highly tunable emission by halide engineering in lead-free perovskite-derivative nanocrystals: the Cs2SnX6 (X = Cl, Br/I, I) system,
(2020) Front. Chem., 8, art. no. 35. DOI: 10.3389/fchem.2020.00035